Synovial Fluid Extracellular Vesicles from Patients with Severe Osteoarthritis Differentially Promote a Pro-Catabolic, Inflammatory Chondrocyte Phenotype

Synovial Fluid Extracellular Vesicles from Patients with Severe Osteoarthritis Differentially Promote a Pro-Catabolic, Inflammatory Chondrocyte Phenotype

Synovial inflammation is recognised as a pathological driver of osteoarthritis (OA), a degenerative joint disease involving cartilage degradation and joint pain. Since extracellular vesicles (EVs) have emerged as key mediators of cellular cross-talk, this study characterised synovial fluid EVs (SFEV...

Full description

Saved in:
Bibliographic Details
Main Authors: Caitlin Ditchfield, Joshua Price, Edward T. Davis, Simon W. Jones
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
osteoarthritis
extracellular vesicles
synovial fluid
articular chondrocytes
synovitis
Online Access:https://www.mdpi.com/2218-273X/15/6/829
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items