Alpha-synuclein null mutation exacerbates the phenotype of a model of Menkes disease in female mice

Human SNCA, which encodes a-synuclein protein (SNCA), was the first gene linked to familial Parkinson’s disease (PD). Since the discovery of the genetic link of SNCA to Parkinson’s nearly three decades ago, many studies have investigated the normal function of SNCA protein. However, understanding of...

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Bibliographic Details
Main Authors: MegAnne Casey, Dan Zou, Renee A. Reijo Pera, Tiffany Hensley-McBain, Deborah E. Cabin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1613171/full
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