Targeted protein degradation with small molecules for cancer immunotherapy

Immunotherapy has transformed cancer treatment, marked by the approval of numerous antibody-based drugs. However, the limitations of antibodies in pharmacokinetics including long half-lives, limited oral bioavailability and immunogenicity, have prompted the pursuit of small molecule-based immunother...

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Bibliographic Details
Main Authors: Zichao Yang, Jianwei Xu, Xixiang Yang, Jianjun Chen
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Asian Journal of Pharmaceutical Sciences
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Online Access:http://www.sciencedirect.com/science/article/pii/S181808762500042X
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