The Effects of High-Dose Probiotic Supplementation on Immune Activation and Neurocognitive Disorders in People Living with HIV Undergoing Successful Antiretroviral Treatment: The Procog Study

The Effects of High-Dose Probiotic Supplementation on Immune Activation and Neurocognitive Disorders in People Living with HIV Undergoing Successful Antiretroviral Treatment: The Procog Study

Background: The prevalence of HIV-associated neurocognitive disorders (HAND) remains high despite antiretroviral treatment (ART). Changes in gut microbiota and persistent immune activation have been suggested as possible causes, while the role of probiotic supplementation remains controversial. Meth...

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Main Authors: Matteo Vassallo, Margaux Zerlini, Roxane Fabre, Heloise Joly, Jacques Durant, Alain Makinson, Amandine Mauries, Jacqueline Capeau, Soraya Fellahi, Jean-Philippe Bastard, Christian Pradier, Christine Lebrun-Frenay
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pathogens
Subjects:
HIV-associated neurocognitive disorders
probiotics
gut microbiota
immune activation
Online Access:https://www.mdpi.com/2076-0817/14/6/568
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