Functional aptamer evolution-enabled elucidation of a melanoma migration-related bioactive epitope

Functional aptamer evolution-enabled elucidation of a melanoma migration-related bioactive epitope

Metastasis is the leading cause of death from cutaneous melanoma. Identifying metastasis-related targets and developing corresponding therapeutic strategies are major areas of focus. While functional genomics strategies provide powerful tools for target discovery, investigations at the protein level...

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Bibliographic Details
Main Authors: Hong Xuan, Siqi Bian, Qinguo Liu, Jun Li, Shaojin Li, Sharpkate Shaker, Haiyan Cao, Tongxuan Wei, Panzhu Yao, Yifan Chen, Xiyang Liu, Ruidong Xue, Youbo Zhang, Liqin Zhang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
FAETI
Aptamer
Melanoma migration
Phenotype screening
Target and epitope discovery
CSPG4
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525001212
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