TREM2 in MASH: integrating lipid metabolism and immune response

TREM2 in MASH: integrating lipid metabolism and immune response

Metabolic dysfunction-Associated Steatohepatitis (MASH), a progressive liver disease characterized by disturbances of lipid metabolism and chronic inflammation response in liver has become the most prevalent chronic liver diseases worldwide. Recent single-cell transcriptomic studies in both humans a...

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Bibliographic Details
Main Authors: Shuyi Shi, Yangyang Zhou, Haiming Zhang, Junli Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
metabolic dysfunction -associated steatohepatitis (MASH)
triggering receptor expressed on myeloid cells-2 (TREM2)
lipid-associated macrophages (LAMs)
lipid metabolism
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1604837/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1604837/full

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