Smurf2 knockdown attenuates the progression of diabetic nephropathy by inhibiting mesangial cell proliferation and fibrosis through suppressing EYA2 ubiquitination

Diabetic nephropathy (DN) is a serious microvascular complication of diabetes and the main cause of end-stage renal disease. Smurf2 is a member of ubiquitin ligases. In this study, we aimed to investigate the mechanism by which Smurf2 mediated the development of DN. C57BL/6 mice were intraperitoneal...

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Bibliographic Details
Main Authors: Lizhen Chen, Yuqing Chen, Fei Liu, Yinhao Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
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Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2520904
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