Experimental assessment of ladasten and GB-115 effects on the antinociceptive tolerance to morphine

The development of morphine-induced antinociceptive tolerance limits its therapeutic efficacy in pain management. Effects of non-benzodiazepine anxiolytics ladasten and GB-115 on the development of antinociceptive tolerance to morphine were studied in albino male rats. The tolerance was induced by d...

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Bibliographic Details
Main Authors: M. A. Konstantinopolsky, I. V. Chernyakova, L. G. Kolik
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2016-03-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/173
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