Temperature Cycle-Induced Deracemization of Cl-TAK Using Amberlyst A26: A Heterogeneous Catalyst Approach for Efficient and Reusable Racemization

Temperature Cycle-Induced Deracemization of Cl-TAK Using Amberlyst A26: A Heterogeneous Catalyst Approach for Efficient and Reusable Racemization

This study investigates the feasibility of employing Amberlyst A26 as a racemizing agent for the temperature cycle-induced deracemization (TCID) of the model compound Cl-TAK (1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl) pentan-3-one). We assessed Amberlyst A26 for its potential as a reu...

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Bibliographic Details
Main Authors: Jin Maeda, Pascal Cardinael, Gerard Coquerel, Adrian Flood
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Chemistry Proceedings
Subjects:
temperature cycle-induced deracemization
Amberlyst A26
heterogeneous catalysis
racemization
enantiomeric excess
Online Access:https://www.mdpi.com/2673-4583/15/1/4
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https://www.mdpi.com/2673-4583/15/1/4

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