The association between triglyceride-glucose index, atherogenic index of plasma, systemic immune-inflammation index, and mortality in patients with acute coronary syndrome: the direct effects of glucose-lipid metabolism and U-shaped immune modulation in mortality risk

The association between triglyceride-glucose index, atherogenic index of plasma, systemic immune-inflammation index, and mortality in patients with acute coronary syndrome: the direct effects of glucose-lipid metabolism and U-shaped immune modulation in mortality risk

BackgroundCardiovascular disease (CVD) remains the leading global cause of death, with inflammation and glycolipid dysregulation as key drivers of atherosclerosis progression. While triglyceride-glucose index (TyG) and Atherogenic Index of Plasma (AIP) are linked to cardiovascular risk, their progno...

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Main Authors: Weichen Luo, Zaixiao Tao, Xinxin Li, Yang Xu, Chun Yang, Rui Sun, Mi Wang, Zhenjun Ji, Genshan Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
glucolipid metabolism
inflammation
nonlinear relationship
acute coronary syndrome
triglyceride-glucose index
atherogenic index of plasma
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1604284/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1604284/full

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