Integration of phospho-signaling and transcriptomics in single cells reveals distinct Th17 cell fates

Integration of phospho-signaling and transcriptomics in single cells reveals distinct Th17 cell fates

Summary: Single-cell RNA sequencing (scRNA-seq) provides the resolution and scale necessary to identify transcriptional programs but fails to capture post-transcriptional information critical to decipher signaling networks and cellular states. We present Vivo-seq, an innovative platform that integra...

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Main Authors: Seth D. Fortmann, Awalpreet S. Chadha, Blake F. Frey, Asif Elahi, Vidya Sagar Hanumanthu, Shanrun Liu, Andrew Goldsborough, P. Brent Ferrell, Jr., Maria B. Grant, Casey T. Weaver, Robert S. Welner
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725007776
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http://www.sciencedirect.com/science/article/pii/S2211124725007776

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