STUDY OF THE EFFECT OF STRUCTURE ON OCTANOL-WATER DISTRIBUTION OF 6-HYDROXYPYRIMIDINE-4-(<i>3H</i>)-ONES DERIVATIVES
The results of an experimental study of the effect of structure of substituting groups and pH value on the partition coefficients in biphasic systems of n-octanol and water for a number of 2,5-substituted 6-hydroxypyrimidine-4-(3H)-ones are presented.
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Main Authors: | A. E. Potapova, A. A. Teslev |
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Format: | Article |
Language: | Russian |
Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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Series: | Разработка и регистрация лекарственных средств |
Subjects: | |
Online Access: | https://www.pharmjournal.ru/jour/article/view/426 |
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