TET3 regulates hematopoietic stem cell homeostasis during embryonic and adult hematopoiesis

ABSTRACT The ten‐eleven translocation family of enzymes (TET1/2/3) promotes DNA demethylation and is essential for hematopoiesis. While the roles of TET1 and TET2 are well‐studied in hematopoiesis, the requirement of TET3 in embryonic and adult hematopoiesis is less investigated. In this study, by c...

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Bibliographic Details
Main Authors: Harmony C. Ketchum, Claudia Morganti, Chie Yanase, Blake Ebert, Keisuke Ito, Meelad M. Dawlaty
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:HemaSphere
Online Access:https://doi.org/10.1002/hem3.70140
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