Alternative cleavage and polyadenylation: key regulatory mechanisms in health and disease

Alternative polyadenylation (APA) is a critical post-transcriptional regulatory mechanism that generates diverse mRNA isoforms by selecting different polyadenylation sites within pre-mRNAs, thereby modulating the length of the 3’ untranslated region (3’ UTR), thereby fine-tuning gene expression and...

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Bibliographic Details
Main Authors: Ying Zhang, Zikun Huang, Weiqing Lu, Zhaoyong Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:RNA Biology
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Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2025.2529033
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