Druggability, molecular targets, and nanocarrier delivery of natural triterpenoid celastrol against chronic diseases

Celastrol is an active compound from the root of Tripterygium wilfordii Hook F that shows great potential in the treatment of inflammation, cancer, neurodegeneration, diabetes, and obesity. However, the clinical application of celastrol has been hindered by its low bioavailability and severe syste...

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Bibliographic Details
Main Authors: Chi Lui Chan, Yilu Sun, Xiaowen Mao, Hansen Chen, Jia Zhao, Jianhui Rong
Format: Article
Language:English
Published: Compuscript Ltd 2024-10-01
Series:Acta Materia Medica
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0044
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