Development of Human Skin Equivalents with Inducible Ceramide Depletion for In Vitro Modeling of Lipid Impairment
The lipid composition of the epidermis plays a critical role in the skin’s barrier function, and defects in lipid synthesis or assembly can cause a spectrum of skin diseases, ranging from dry skin to severe ichthyoses. The aim of this study was to develop an in vitro model of human skin with tunable...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-07-01
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Series: | JID Innovations |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667026725000396 |
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