An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

Accurate identifying internal tandem duplication (ITD) mutation is indispensable for diagnosis and prognosis of acute myeloid leukemia (AML) patients, but specialized full-size detection tools are lacking. Therefore, we aimed to develop a reliable system for accurate assessment of ITD mutations of v...

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Bibliographic Details
Main Authors: Li-Li Zhang, Zhe Wang, Ying Zhou, Dai-Yang Li, Xiao-Nian Tu, Yu-Xia Li, Ke-Ming Du, Zhong-Zheng Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Experimental Biology and Medicine
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Online Access:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10128/full
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