Genomic profiling of cefotaxime-resistant Haemophilus influenzae from Norway and Sweden reveals extensive expansion of virulent multidrug-resistant international clones

Genomic profiling of cefotaxime-resistant Haemophilus influenzae from Norway and Sweden reveals extensive expansion of virulent multidrug-resistant international clones

Cefotaxime-resistant Haemophilus influenzae (CRHI) are a global concern, but little is known about their molecular epidemiology. The goal of this study was to perform genomic profiling of 191 CRHI from Norway (n = 183) or Sweden (n = 8) (2006–2018) and assess clonal spread using core genome multiloc...

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Main Authors: Dagfinn Skaare, Inger Lill Anthonisen, Nermin Zecic, Andrew Jenkins, Dominique A. Caugant, Trond Egil Ranheim, Arnfinn Sundsfjord, Kristin Hegstad, Study Group on Exceptional Phenotypes in Haemophilus influenzae, Truls Michael Leegaard, Tine Smedsund Dons, Paul Christoffer Lindemann, Karianne Wiger Gammelsrud, Kjersti Wik Larssen, Iren Høyland Löhr, Kyriakos Zaragkoulias, Roar Magne Bævre-jensen, Sara Debes, Reidar Hjetland, Annika Carlsson Wistedt, Ståle Tofteland, Liv Jorunn Hafne, Gunnar Skov Simonsen, Einar Nilsen, Brynja Ármannsdóttir, Martin Sundqvist, Anna Åkerlund, Carina Thilesen, Sandra Åsheim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
PBP3
ftsI
CRHI
BLNAR
BLPACR
cgMLST
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1601390/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1601390/full

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