The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis

The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis

BackgroundApical periodontitis (AP) is a highly prevalent inflammatory condition that affects the tissue surrounding the apex of a tooth root. 7ND protein, a mutant form of monocyte chemoattractant protein-1 (MCP-1), functions as a dominant negative inhibitor of MCP-1. Previous studies have shown th...

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Bibliographic Details
Main Authors: Zhang-Zhang Ji, Xiu-Min Xu, Yu-Lin Lu, Run-Zhen Zhang, Ying Zhang, Zhi-Hui Zou, Qi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
monocyte chemoattractant protein-1
7ND
osteoclasts
apical periodontitis
osteolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1597604/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1597604/full

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