Multiaxial rotational loading compromises the transition zone of the intervertebral disc: Ex vivo study using next‐generation bioreactors

Multiaxial rotational loading compromises the transition zone of the intervertebral disc: Ex vivo study using next‐generation bioreactors

Abstract Bioreactors have become indispensable tools in spine research, enabling long‐term intervertebral disc culture under controlled biological and mechanical conditions. Conventional systems are often limited to uniaxial loading, restricting their ability to replicate the complex, multidirection...

Full description

Saved in:
Bibliographic Details
Main Authors: Amra Šećerović, Aapo Ristaniemi, Francesco Crivelli, Sarah Heub, Mauro Alini, Gilles Weder, Diane Ledroit, Stephen J. Ferguson, Sibylle Grad
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Bioengineering & Translational Medicine
Subjects:
bioreactors
intervertebral disc
multiaxial loading
transition zone
whole organ culture
Online Access:https://doi.org/10.1002/btm2.70033
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items