Structural characterization of stem cell factors Oct4, Sox2, Nanog and Esrrb disordered domains, and a method to detect phospho-dependent binding partners
The combined expression of a handful of pluripotency transcription factors (PluriTFs) in somatic cells can generate induced pluripotent stem cells (iPSCs). Here, we report the structural characterization of disordered regions contained in four important PluriTFs, namely Oct4, Sox2, Nanog and Esrrb....
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Main Authors: | Bouguechtouli, Chafiaa, Ghouil, Rania, Alik, Ania, Dingli, Florent, Loew, Damarys, Theillet, Francois-Xavier |
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Format: | Article |
Language: | English |
Published: |
Académie des sciences
2024-04-01
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Series: | Comptes Rendus. Chimie |
Subjects: | |
Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.272/ |
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