Management of a potential donor with brain death (PART 1)

The lack of donor organs is the main factor limiting organ transplantation. Currently, the majority of transplants are taken from brain-dead donors. In most cases the brain death is associateed with a severe physiologic instability that may deteriorate the donor organ function prior to the excision...

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Bibliographic Details
Main Author: V. L. Vinogradov
Format: Article
Language:English
Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 2016-02-01
Series:Трансплантология (Москва)
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Online Access:https://www.jtransplantologiya.ru/jour/article/view/89
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Summary:The lack of donor organs is the main factor limiting organ transplantation. Currently, the majority of transplants are taken from brain-dead donors. In most cases the brain death is associateed with a severe physiologic instability that may deteriorate the donor organ function prior to the excision or lead to the loss of the donor. An active or even aggressive management of a donor allows the control and correction of pathophysiological processes in donor organs, thus increasing the number and improving the functional condition of donor organs.An aggressive management strategy for a potential donor with brain death requires to change both the approach to intensive care, and the philosophic aspect in the evaluation of this work. Despite the development and implementation of various protocols for brain-dead donors, an optimum combination of objectives, monitoring, specific therapy has not been worked out yet.
ISSN:2074-0506
2542-0909