Soluble CD127 potentiates IL‐7 activity in vivo in healthy mice

Abstract Introduction Soluble forms of cytokine receptors can be involved in the endogenous regulation of cytokine activity. Soluble interleukin 7 receptor α (sCD127) naturally binds IL‐7, therefore there is interest in its potential application as an immunotherapeutic agent to regulate IL‐7. With t...

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Bibliographic Details
Main Authors: Nawaf A. Aloufi, Alaa K. Ali, Stephanie C. Burke Schinkel, Bengisu Molyer, Priscila O. Barros, Joanne E. McBane, Seung‐Hwan Lee, Jonathan B. Angel
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Immunity, Inflammation and Disease
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Online Access:https://doi.org/10.1002/iid3.530
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