Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report

Cladophialophora boppii is a dematiaceous fungus rarely causing cutaneous and respiratory infections. We present a case of deep cutaneous infection in a 69-year-old patient in the Netherlands with stage IV breast cancer on dexamethasone therapy. The patient exhibited a skin plaque lesion, and biopsy...

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Main Authors: Thuy Thanh Cavens, Janneke de Vries, Suzanne Verleisdonk-Bolhaar, Jochem B. Buil, Arienne van Marion
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Medical Mycology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211753925000260
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Summary:Cladophialophora boppii is a dematiaceous fungus rarely causing cutaneous and respiratory infections. We present a case of deep cutaneous infection in a 69-year-old patient in the Netherlands with stage IV breast cancer on dexamethasone therapy. The patient exhibited a skin plaque lesion, and biopsy revealed pigmented, septate hyphae without muriform cells, consistent with a diagnosis of phaeohyphomycosis. Surgical excision and culture confirmed C. boppii. Afterwards the patient received a three-week course of itraconazole, which led to infection resolution. This report and review of literature underscores the diagnostic and therapeutic approaches for managing deep cutaneous infections caused by C. boppii.
ISSN:2211-7539