Construction of an El Tor Biovariant Vibrio cholerae Strain Capable of Type II Cholera Toxin Hyperproduction and Determining the Optimal Conditions for the Production of This Protein

Construction of an El Tor Biovariant Vibrio cholerae Strain Capable of Type II Cholera Toxin Hyperproduction and Determining the Optimal Conditions for the Production of This Protein

Introduction of Tn5-Mob (KmR) transposon into the chromosome of the toxinogenic V. cholerae strain MAK757 El Tor biovar was shown to result in the emergence of insertion mutants containing an altered genome of CTXφ prophage. The reorganization ofthe latter was expressed in the deletion of four genes...

Full description

Saved in:
Bibliographic Details
Main Authors: A. A. Goryaev, E. Yu. Shchelkanova, Yu. V. Lozovsky, I. V. Touchkov, N. I. Smirnova
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2008-02-01
Series:Проблемы особо опасных инфекций
Subjects:
the cholera agent
a cholera toxin hyperproducing strain
prophage ctxφ genome reorganization
tn5-mob transposon
Online Access:https://journal.microbe.ru/jour/article/view/1075
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items