Review of existing methodologies to assess the activity of CYP2D6 using exogenous and endogenous markers

Peculiarities of functioning and polymorphism of cytochrome P450 isoenzyme CYP2D6. Existing methods for determining its activity using endogenous markers. A review of studies on the screening of endogenous substrates, biotransformation mainly under the influence of isoenzyme CYP2D6. The results by d...

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Bibliographic Details
Main Authors: A. D. Abdrashitov, G. N. Gildeeva, G. V. Ramenskaya, V. V. Smirnov
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2014-04-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/147
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