Wnt/PKC Signaling Inhibits Sensory Hair Cell Formation in the Developing Mammalian Cochlea

Wnt/PKC Signaling Inhibits Sensory Hair Cell Formation in the Developing Mammalian Cochlea

The establishment of cell fate and boundaries between cell types is an essential step in development and organogenesis. In the mammalian cochlea, a distinct boundary exists between a medial region of non-sensory cells and a lateral region of sensory cells. We report that Wnt4 and sFRP2 act in combin...

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Bibliografiska uppgifter
Huvudupphovsmän: Joanna F. Mulvaney, Erynn M. Layman, Farhana Feroze-Merzoug, Julia M. Abitbol, Jennifer M. Jones, Dara O’Connor, Florence Naillat, Seppo Vainio, Jeffrey S. Rubin, Matthew W. Kelley, Alain Dabdoub
Materialtyp: Artikel
Språk:engelska
Publicerad: MDPI AG 2025-06-01
Serie:Cells
Ämnen:
mouse
hearing
cochlea
genes
hair cell
Länkar:https://www.mdpi.com/2073-4409/14/12/888
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