Wnt/PKC Signaling Inhibits Sensory Hair Cell Formation in the Developing Mammalian Cochlea

The establishment of cell fate and boundaries between cell types is an essential step in development and organogenesis. In the mammalian cochlea, a distinct boundary exists between a medial region of non-sensory cells and a lateral region of sensory cells. We report that Wnt4 and sFRP2 act in combin...

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Auteurs principaux: Joanna F. Mulvaney, Erynn M. Layman, Farhana Feroze-Merzoug, Julia M. Abitbol, Jennifer M. Jones, Dara O’Connor, Florence Naillat, Seppo Vainio, Jeffrey S. Rubin, Matthew W. Kelley, Alain Dabdoub
Format: Article
Langue:anglais
Publié: MDPI AG 2025-06-01
Collection:Cells
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Accès en ligne:https://www.mdpi.com/2073-4409/14/12/888
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