Replication differences of SARS-CoV-2 lineages may arise from unique RNA replication characteristics and nucleocapsid protein expression

Replication differences of SARS-CoV-2 lineages may arise from unique RNA replication characteristics and nucleocapsid protein expression

IntroductionThe COVID-19 pandemic was characterized by the sequential introduction and circulation of distinct SARS-CoV-2 variants, which presented differences in transmission capacity and pathogenicity. However, the relationship between these differences and the replicative capacity of these varian...

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Main Authors: Isadora Alonso Corrêa, Marcos Romário Matos de Souza, Gustavo Peixoto Duarte da Silva, Anna Beatriz Sampaio Vianna Macedo Pimentel, Pedro Telles Calil, Marcela Sabino Cunha, Diana Mariani, Rodrigo de Moraes Brindeiro, Sara Mesquita Costa, Maria Clara da Costa Simas, Victor Akira Ota, Elisa Cavalcante Pereira, Marilda Mendonça Siqueira, Paola Cristina Resende, Rafael Mello Galliez, Debora Souza Faffe, Rosane Silva, Terezinha Marta Pereira Pinto Castiñeiras, Amilcar Tanuri, Luciana Jesus da Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
SARS-CoV-2
variants
replication
virus-cell interaction
RNA replication
nucleocapsid protein
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1582137/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1582137/full

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