Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse.

Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse.

Viruses capable of causing persistent infection have developed sophisticated mechanisms for evading host immunity, and understanding these processes can reveal novel features of the host immune system. One such virus, human pegivirus (HPgV), infects ~15% of the global human population, but little is...

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Main Authors: Kylie Nennig, Satyapramod Murthy, Sara Maloney, Teressa M Shaw, Mark Sharobim, Eduard Matkovic, Simi Fadiran, Malorie Larsen, Mitchell D Ramuta, Arthur S Kim, John R Teijaro, Joe Grove, Matthew Stremlau, Himanshu Sharma, Sheetal Trivedi, Michael J Blum, David H O'Connor, Jennifer L Hyde, Jack T Stapleton, Amit Kapoor, Adam L Bailey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012436
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https://doi.org/10.1371/journal.ppat.1012436

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