Case Report: Malignant transformation of maxillary giant cell tumor of bone from EURACAN reference center

Giant cell tumor of bone (GCTB) is a benign but locally aggressive neoplasm that can rarely undergo malignant transformation, with a poor prognosis. The most frequent histotypes of the sarcomatous transformation of GCTB are osteosarcoma, fibrosarcoma, and undifferentiated pleomorphic sarcoma, and th...

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Main Authors: Federica Riva, Sabrina Vari, Concetta Elisa Onesti, Renato Covello, Silvia Scuderi, Serena Ceddia, Maria Rosaria Fiore, Vincenzo Anelli, Sabino Strippoli, Virginia Ferraresi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1604056/full
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