ELABELA Ameliorates Atherosclerosis Through Restoring the M1/M2 Macrophage Balance in ApoE−/− Mice

Background Atherosclerosis is a progressive arterial disease characterized by chronic inflammation and plaque formation in blood vessel walls. ELABELA, an endogenous ligand for the G protein‐coupled receptor APJ (apelin peptide jejunum, apelin receptor), has multiple pharmacological activities for p...

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Main Authors: Le Tang, Xiaoli Yi, Wenting Tan, Huiru Yang, Shanshan Song, Jianhua Xiong, Chunju Liu, Yifeng Zhang, Mulan Wang, Mengzhi Zhu, Lixiang Zheng, Jun Yu, Chuanming Xu
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
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Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.041261
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