TEAD4 Transcriptionally Activates TRIB3 to Induce Ferroptosis Resistance through the MEK/ERK Signaling Pathway in Colorectal Cancer

TEAD4 Transcriptionally Activates TRIB3 to Induce Ferroptosis Resistance through the MEK/ERK Signaling Pathway in Colorectal Cancer

Background/Aims : Colorectal cancer (CRC) is the third most prevalent malignancy and the second leading cause of cancer-associated death worldwide. Ferroptosis is a form of regulated cell death that has been linked to the treatment of CRC. Tribbles homolog 3 (TRIB3) and TEA domain transcription fact...

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Bibliographic Details
Main Authors: Jianguo Wang, Xiangbo Wu
Format: Article
Language:English
Published: Gastroenterology Council for Gut and Liver 2025-07-01
Series:Gut and Liver
Subjects:
colorectal neoplasms; tribbles pseudokinase 3; ferroptosis; map kinase signaling system; transcriptional enhanced associate domain 4 protein
Online Access:http://gutnliver.org/journal/view.html?doi=10.5009/gnl240439
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http://gutnliver.org/journal/view.html?doi=10.5009/gnl240439

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