Dysregulated cancer cell transdifferentiation into erythrocytes is an additional metabolic stress in hepatocellular carcinoma

A number of human and canine hepatocellular carcinoma tissues showed clear signs of hypoxia indicated by HIF1α-activation and the presence of large clusters of cells resembling erythrocytes at different stages of nuclear elimination without any defined endothelial cell lining or blood vessel walls....

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Bibliographic Details
Main Authors: Abigail Hughes, Gurtej K Dhoot
Format: Article
Language:English
Published: SAGE Publishing 2018-11-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428318811467
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