Pathogenetic therapy of mitral valve prolapse

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Pathogenetic therapy of mitral valve prolapse

Aim. To evaluate the effect of angiotensin II receptor blocker (ARB) therapy on the expression of transforming growth factor-β (TGF-β) in the myxomatous mitral valve, on the serum levels of TGF-β1/TGF-β2 and the left ventricular (LV) systolic function in patients with mitral valve prolapse (MVP).Mat...

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Bibliographic Details
Main Authors:	E. G. Malev, S. V. Reeva, M. Yu. Omelchenko, L. B. Mitrofanova, E. V. Timofeev, N. N. Parfenova, E. B. Luneva
Format:	Article
Language:	Russian
Published:	«FIRMA «SILICEA» LLC 2025-02-01
Series:	Российский кардиологический журнал
Subjects:	angiotensin ii receptor blockers mitral valve prolapse myxomatous degeneration mitral regurgitation mitral valve surgery left ventricular strain transforming growth factor-β type iii collagen fibulin-5 valve interstitial cells
Online Access:	https://russjcardiol.elpub.ru/jour/article/view/5948
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