Pathogenetic therapy of mitral valve prolapse

Pathogenetic therapy of mitral valve prolapse

Aim. To evaluate the effect of angiotensin II receptor blocker (ARB) therapy on the expression of transforming growth factor-β (TGF-β) in the myxomatous mitral valve, on the serum levels of TGF-β1/TGF-β2 and the left ventricular (LV) systolic function in patients with mitral valve prolapse (MVP).Mat...

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Bibliographic Details
Main Authors: E. G. Malev, S. V. Reeva, M. Yu. Omelchenko, L. B. Mitrofanova, E. V. Timofeev, N. N. Parfenova, E. B. Luneva
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2025-02-01
Series:Российский кардиологический журнал
Subjects:
angiotensin ii receptor blockers
mitral valve prolapse
myxomatous degeneration
mitral regurgitation
mitral valve surgery
left ventricular strain
transforming growth factor-β
type iii collagen
fibulin-5
valve interstitial cells
Online Access:https://russjcardiol.elpub.ru/jour/article/view/5948
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