Complement C3 inhibition reduces complement activation in clinical platelet concentrates but does not counteract platelet storage lesions

Platelet storage is associated with storage lesions, including platelet morphological changes and a gradual functional loss. We investigated the impact of complement C3 inhibition on complement activation and platelet storage lesions in clinical platelet concentrates. Platelet concentrates (n = 8) w...

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Bibliographic Details
Main Authors: Linnea I. Andersson, Per Sandgren, Dick J. Sjöström, Camilla Mohlin, Kim Hägerström, Ivar Tjernberg, Tom Eirik Mollnes, Per H. Nilsson
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Platelets
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Online Access:https://www.tandfonline.com/doi/10.1080/09537104.2025.2513298
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