A spatial imaging-transcriptomics paradigm for deciphering the molecular basis of microscopic MRI in the normal brain and Alzheimer’s disease

Summary: Imaging genomics offers powerful links between genetics and neuroimaging phenotypes, but conventional methods often lack spatial correspondence. We introduce spatial imaging-transcriptomics, a paradigm that directly integrates magnetic resonance imaging (MRI) and spatially resolved transcri...

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Main Authors: Yiqi Shen, Yao Shen, Menglei Wang, Kaiyu Jin, Penghui Yang, Zuozhen Cao, Qinfeng Zhu, Zhiyong Zhao, Haotian Li, Lei Han, Shiping Liu, Jie Liao, Jing Zhang, Xiaohui Fan, Dan Wu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725008447
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