DNA Methylation of <i>Igf2r</i> Promoter CpG Island 2 Governs <i>Cis</i>-Acting Inheritance and Gene Dosage in Equine Hybrids
Genomic imprinting is critical for mammalian development, but its regulation varies across species. The insulin-like growth factor 2 receptor (IGF2R), which is a maternally expressed imprinted gene critical for cell proliferation and differentiation, as well as embryonic and placental development, i...
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Main Authors: | Xisheng Wang, Yingchao Shen, Hong Ren, Minna Yi, Gerelchimeg Bou |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-06-01
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Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/14/6/678 |
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