Using transcriptome Shannon entropy to evaluate the off-target effects and safety of insecticidal siRNAs

Using transcriptome Shannon entropy to evaluate the off-target effects and safety of insecticidal siRNAs

A recent breakthrough in agricultural biotechnology is the introduction of RNAi-mediated strategies in pest control. However, the off-target effects of RNAi pest control are still not fully understood. Here, we studied the off-target effects of two insecticidal siRNAs in both target and non-target i...

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Bibliographic Details
Main Authors: Wei-hua MA, Tong WU, Zan ZHANG, Hang LI, Gong-ming SITU, Chuan-lin YIN, Xin-hai YE, Meng-yao CHEN, Xian-xin ZHAO, Kang HE, Fei LI
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Journal of Integrative Agriculture
Subjects:
RNAi
off-target effect
transcriptome entropy
non-target organisms
RNAi-mediated pest management
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311920633949
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http://www.sciencedirect.com/science/article/pii/S2095311920633949

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