Synthesis of Dimethyl (<i>Z</i>)-((3-oxoindolin-2-ylidene) (aryl)methyl)phosphonates Through Tandem Cadogan and Arbuzov Reactions

Synthesis of Dimethyl (<i>Z</i>)-((3-oxoindolin-2-ylidene) (aryl)methyl)phosphonates Through Tandem Cadogan and Arbuzov Reactions

A novel method employing a tandem Cadogan and Arbuzov reaction sequence has been developed, providing access to a series of previously unreported dimethyl (Z)-((3-oxoindolin-2-ylidene)(aryl)methyl)phosphonates. Restricted rotation of the aryl substituent, particularly in the presence of <i>ort...

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Bibliographic Details
Main Authors: Nicolai A. Aksenov, Dmitrii A. Aksenov, Daniil D. Ganusenko, Alexander E. Kurlikov, Alexander P. Barbolin, Polina S. Karaseva, Alexander V. Aksenov
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molbank
Subjects:
Cadogan–Sundberg reaction
Arbuzov reaction
chalcones
reduction
indoles
phosphites
Online Access:https://www.mdpi.com/1422-8599/2025/2/M2002
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https://www.mdpi.com/1422-8599/2025/2/M2002

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