Understanding Bio-Orthogonal Strain-Driven Sydnone Cycloadditions: Data-Assisted Profiles and the Search for Linear Relationships

In the realm of click-type reactions and their application to bioorthogonal chemistry in living organisms, metal-free [3+2] cycloadditions involving mesoionic rings and strained cycloalkynes have gained increasing attention and potentiality in recent years. While there has been a significant accreti...

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Bibliographic Details
Main Authors: Juan García de la Concepción, Pedro Cintas, Rafael Fernando Martínez
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/30/13/2770
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