Impact of Hematopoietic Stem Cell Transplantation on PD-1 Blockade Efficacy in Relapsed/Refractory Hodgkin’s Lymphoma

Impact of Hematopoietic Stem Cell Transplantation on PD-1 Blockade Efficacy in Relapsed/Refractory Hodgkin’s Lymphoma

Background: Classical Hodgkin lymphoma (cHL) is a treatable malignancy; however, relapsed or refractory (R/R) cases pose significant challenges. PD-1 inhibitors have shown efficacy, but the role of hematopoietic stem cell transplantation (HSCT) following PD-1 blockade remains uncertain. This study a...

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Main Authors: Filomena Emanuela Laddaga, Pierluigi Masciopinto, Valentina Bozzoli, Domenico Pastore, Vincenzo Pavone, Angelo Michele Carella, Nicola Di Renzo, Attilio Guarini, Pellegrino Musto, Francesco Gaudio
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Transplantology
Subjects:
classical Hodgkin lymphoma (cHL)
PD-1 blockade
hematopoietic stem cell transplantation (HSCT)
relapsed/refractory (R/R) lymphoma
progression-free survival (PFS)
Online Access:https://www.mdpi.com/2673-3943/6/2/12
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https://www.mdpi.com/2673-3943/6/2/12

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