Synthesis of DOTA-Based <sup>43</sup>Sc Radiopharmaceuticals Using Cyclotron-Produced <sup>43</sup>Sc as Exemplified by [<sup>43</sup>Sc]Sc-PSMA-617 for PSMA PET Imaging

The implementation of theranostics in oncologic nuclear medicine has exhibited immense potential in improving patient outcomes in prostate cancer with the implementation of [<sup>68</sup>Ga]Ga-PSMA-11 PET and [<sup>177</sup>Lu]Lu-PSMA-617 into clinical practice. However, the...

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Main Authors: Jason P. Meier, Mohammed Bhuiyan, Richard Freifelder, Hannah J. Zhang, Lucas Gonzalez, Antonino Pusateri, Hsiu-Ming Tsai, Lara Leoni, Kaustab Ghosh, Erica Markiewicz, Christopher Henning, Yuhan Zhang, Ralph Weichselbaum, Jerry Nolen, David A. Rotsch, Chien-Min Kao, Russell Z. Szmulewitz, Chin-Tu Chen, Satish K. Chitneni
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Methods and Protocols
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Online Access:https://www.mdpi.com/2409-9279/8/3/58
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