The Impact of Enzyme-Replacement Therapy on Upper Airway Obstruction in Children with Mucopolysaccharidoses: Retrospective Cohort Study

The Impact of Enzyme-Replacement Therapy on Upper Airway Obstruction in Children with Mucopolysaccharidoses: Retrospective Cohort Study

Background. Data on the efficacy of enzyme replacement therapy (ERT) in relation to the pathology of ENT organs and respiratory performance in sleep in children with mucopolysaccharidosis (MPS) is poorly presented in the literature. Our aim was to assess the effect of ERT on the upper respiratory tr...

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Main Authors: Liliya A. Osipova, Ludmila M. Kuzenkova, Leyla S. Namazova-Baranova, Anait K. Gevorkyan, Tatiana V. Podkletnova, Viktor V. Altunin, Olga V. Kozhevnikova, Liya V. Toropchina, Tatiana A. Polunina, E. V. Zelenkova, Nato D. Vashakmadze
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2018-05-01
Series:Педиатрическая фармакология
Subjects:
children
mucopolysaccharidosis
enzyme replacement therapy
airway obstruction
apnea-hypopnea index
hypertrophy of palatine tonsils
hypertrophy of adenoids
Online Access:https://www.pedpharma.ru/jour/article/view/1615
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