Proliferation and regeneration of the healthy human urothelium: A multi-scale simulation approach with 16 hypotheses of cell differentiation.

The urothelium as a stratified epithelium of the urinary tract is a slow regenerating tissue of different layers and shares similarities with the epidermis. Characteristics of its cell types, regeneration, tissue homeostasis, integrity and self organization are only partly understood. Precise comput...

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Bibliographic Details
Main Authors: Fabian Siegel, Angelo Torelli, Minca Mattis, Julian Debatin, Philipp Erben, Markus Gumbel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325132
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