Unveiling B7/CD28 family proteins in hepatocellular carcinoma: insights into communication and prognostic significance

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Unveiling B7/CD28 family proteins in hepatocellular carcinoma: insights into communication and prognostic significance

BackgroundImmunotherapy has made remarkable achievements in cancer treatment, but it still faces the challenge of limited response rates in liver cancer therapy. Although there has been extensive research on the role of programmed cell death-ligand 1 (PD-L1) in hepatocellular carcinoma (HCC), our un...

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Bibliographic Details
Main Authors:	Yan Cai, Xiaodi Liu, Tao He, Yangming Xu, Shuxian Chen, Xianliang Tan, Shouchao Wei, Zimeng Wu, Liying Xiao, Baoming Luo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	hepatocellular carcinoma (HCC) tumor immune environment immunotherapy B7/CD28 family members inhibitory B7 family members B7H3
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1583597/full
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