Influence of SARS-CoV-2 variants’ spike glycoprotein and RNA-dependent RNA polymerase (nsp12) mutations on remdesivir docking residues
Rapid emergence and evolution of novel SARS-CoV-2 variants has raised concerns about their potential impact on efficiency of currently available vaccines. Among the most significant target mutations in the virus are those of the spike glycoprotein. Remdesivir, which inhibits the polymerase activity...
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Format: | Article |
Language: | Russian |
Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2022-07-01
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Series: | Медицинская иммунология |
Subjects: | |
Online Access: | https://www.mimmun.ru/mimmun/article/view/2486 |
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