Amyloid β 1-42 Can Form Ion Channels as Small as Gramicidin in Model Lipid Membranes

The amyloid-beta 1-42 (Aβ1-42) oligomers are the most cytotoxic species of the amyloid family and play a key role in the pathology of Alzheimer’s Disease (AD). They have been shown to damage cellular membranes, but the exact mechanism is complex and not well understood. Multiple routes of membrane d...

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Bibliographic Details
Main Authors: Yue Xu, Irina Bukhteeva, Yurii Potsiluienko, Zoya Leonenko
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Membranes
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Online Access:https://www.mdpi.com/2077-0375/15/7/204
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