A whole-organism landscape of X-inactivation in humans

As females are mosaic for X-inactivation, direct determination of X-linked allelic expression in bulk tissues is typically unfeasible. Using females that are non-mosaic (completely skewed) for X-inactivation (nmXCI) has proven a powerful and natural genetic system for profiling X-inactivation in hum...

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Bibliographic Details
Main Authors: Bjorn Gylemo, Maike Bensberg, Colm E Nestor
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/102701
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